Second, they do not require additional expensive equipment, which is particularly important in areas with limited resources or infrastructure. First, they allow for same-visit diagnosis and immediate counseling and treatment, if indicated. Rapid HSV-2 serologic assays that can be performed on-site with use of blood specimens obtained by fingerstick provide several potential advantages over standard laboratory-based assays. Western blot is considered the gold standard for HSV-2 serologic testing, but because of its cost and limited availability, commercially available type-specific HSV-2 serologic assays are more commonly used for screening. Because most HSV-2 infections are subclinical or unrecognized, serologic testing is often necessary to make a diagnosis after a diagnosis is made, infected patients can be counseled that symptom awareness, condom use, and suppressive treatment may all decrease the risk of transmission to uninfected partners. Appropriate counseling and treatment are predicated on an accurate diagnosis of genital herpes. Genital herpes due to herpes simplex virus type 2 (HSV-2) infection is common and remains underdiagnosed in the United States.
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